Inhibitory Effect of Isoquinoline Alkaloids on Movement of Second-Stage Larvae of Toxocara canis.

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Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canis.

To find new anthelmintics against parasites living in host tissues, we used an in vitro assay to screen isoquinoline alkaloids for nematocidal activity on the larva of dog roundworm, Toxocara canis. To evaluate the efficacy of anthelmintics in vitro, Tsuda et al. previously introduced the concept of Relative Mobility (RM) of Toxocara larvae. After improvement of the assay system using image dat...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2002

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.25.1651